The Surgeon's Notebook | Urology Insights by Mr Denosshan Sri — dsri.co.uk
Writing from the operating theatre

The Surgeon's
Notebook

Evidence-based articles on urological conditions, robotic surgery, and what patients should know

Mr Denosshan Sri  ·  MA Cantab MB BChir FRCS Urol  ·  Consultant Urological Surgeon
Focal therapy for prostate cancer — HIFU, NanoKnife, cryotherapy
Prostate cancer Focal therapy 12 min read August 2026
Focal Therapy Explained — HIFU, IRE/NanoKnife and Cryotherapy

Focal therapy targets the cancer-bearing zone of the prostate rather than the whole gland — potentially preserving urinary and erectile function while maintaining cancer control. This article explains how HIFU, NanoKnife/IRE, and cryotherapy differ, who is a genuine candidate, what 2024 evidence shows about outcomes, and why the follow-up commitment is non-negotiable.

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All articles
Prostate Cancer pathway
Prostate Robotic surgery

The complete diagnostic and treatment pathway — from PSA assessment and mpMRI through to robotic prostatectomy, active surveillance, and survivorship.

February 2025 Read →
Kidney Retroperitoneal RAPN
Kidney cancer Robotic surgery

Why approaching the kidney from behind — without entering the abdominal cavity — can mean faster recovery and better access to posterior tumours. Published personal outcomes included.

March 2025 Read →
Stress urinary incontinence — robotic solutions
Robotic surgery

One in three women experience urinary incontinence. This guide covers the spectrum of treatment — from pelvic floor physiotherapy through to mesh-free robotic colposuspension — in plain language.

November 2025 Read →
Understanding haematuria — blood in urine
General urology

Blood in the urine should always prompt investigation. This guide covers what counts as haematuria, when to act urgently, and what specialist assessment involves from first appointment to diagnosis.

December 2025 Read →
5 ng/mL · PSA
Prostate health

A raised PSA is a signal, not a diagnosis. This article explains what 5 ng/mL means at different ages, the common non-cancer causes, and the step-by-step assessment pathway.

January 2026 Read →
Can a kidney tumour be removed without losing the whole kidney
Kidney cancer

For many kidney tumours, partial nephrectomy preserves the kidney while achieving equivalent cancer control. This article explains who is suitable, how robotic surgery works, and what the decision involves.

February 2026 Read →
Robotic Prostatectomy vs Radiotherapy
Prostate Robotic Surgery

Both treatments offer equivalent cancer control for many men. The choice turns on side effects, recovery, and what trade-offs you can live with — explained clearly and honestly.

April 2026 Read →
Robotic prostatectomy recovery week by week
Prostate Robotic surgery

What really happens after robotic prostatectomy — catheter care, urinary leakage, PSA surveillance, penile rehabilitation, and building confidence through the first two months and beyond.

April 2026 Read →
3 ng/mL  ·  PSA
Prostate health PSA

PSA 3 ng/mL sits in a genuine grey zone — below the classic referral threshold but not automatically reassuring. Age, trend, prostate size, and risk factors all determine what it means for you.

May 2026 Read →
Kidney cyst vs kidney tumour — what's the difference?
Kidney cancer Diagnosis

Most kidney cysts found on scans are entirely harmless. Kidney tumours are different — but many are caught early and highly treatable. This article explains what imaging shows, the Bosniak classification, and when to seek specialist review.

May 2026 Read →
Transperineal prostate biopsy — what is it and does it hurt?
Prostate Diagnosis

The standard approach for prostate sampling in the UK — with lower infection risk than older methods, and usually far more manageable than patients expect. A step-by-step guide to what happens and how to prepare.

May 2026 Read →
HoLEP vs Aquablation vs Rezum vs TURP — which BPH treatment is best for you?
Prostate enlargement BPH New

All four are established BPH treatments — but they are not interchangeable. Prostate size, symptom severity, and priorities around ejaculation all determine which option fits. A plain-language guide to the differences.

May 2026 Read →
Vasectomy — what to expect before, during, and after
General urology

A plain, honest guide to vasectomy — covering the procedure itself, what the recovery involves, when it becomes effective, and what it does not change about sexual function.

May 2026 Read →
Bladder
Cancer
Warning signs & diagnosis
General urology Haematuria

Blood in the urine is the most consistent warning sign of bladder cancer. One episode is enough to justify urgent assessment. This article explains the diagnosis pathway, cystoscopy, TURBT, and how treatment matches stage.

May 2026 Read →
10 ng/mL  ·  PSA
Prostate health PSA

A PSA of 10 ng/mL is above the standard threshold and warrants prompt assessment — but it is not a diagnosis. Age, prostate size, trend, and MRI findings all shape what happens next.

May 2026 Read →
Erectile dysfunction after robotic prostatectomy — recovery and rehabilitation
Prostate Robotic surgery

Erections often take time to recover after radical prostatectomy — and many men need active rehabilitation. This guide explains nerve-sparing, recovery timelines, and the treatments that support erectile function after surgery.

June 2026 Read →
T1a
≤4 cm
T1b
4–7 cm
T2
>7 cm
T3
Spread
Kidney cancer Staging

The T staging letters follow a clear logic once you understand that T1 and T2 measure size, while T3 measures local spread — and a small T3 tumour (with vein involvement) can outrank a much larger T2.

June 2026 Read →
Prostate cancer screening in the UK — PSA testing and high-risk groups
Prostate Screening New

The UK's first targeted prostate cancer screening programme was recommended in June 2026. It covers a tightly defined group. Most high-risk men — including Black men — are still not in a formal programme. Here is what to do.

June 2026 Read →
Focal therapy for prostate cancer — HIFU, NanoKnife and cryotherapy
Prostate Focal therapy New

Focal therapy targets only the cancer-bearing zone of the prostate — potentially reducing side effects compared with whole-gland treatment. This guide explains how each method works, who is a genuine candidate, and what the 2024 evidence shows.

August 2026 Read →
Robotic Retzius-sparing prostatectomy — earlier continence after prostate cancer surgery
Robotic surgery Prostate New

Retzius-sparing prostatectomy uses a posterior surgical approach that preserves front bladder support structures — with consistent evidence for earlier return of urinary continence compared with the standard technique.

August 2026 Read →
Best treatment for a 3cm kidney tumour — partial nephrectomy, surveillance and ablation explained
Kidney cancer Surgery New

Partial nephrectomy is NICE's preferred treatment for a 3cm kidney tumour when feasible — but tumour location changes everything about what is surgically possible. This article explains all options including complex kidney-sparing robotic surgery.

August 2026 Read →
Focal One HIFU for prostate cancer — precision focused ultrasound treatment explained
Prostate Focal therapy New

Focal One HIFU uses robotic, computer-guided focused ultrasound to ablate the cancer-bearing zone of the prostate without removing the whole gland. This article explains how it works, who is genuinely suitable, and how it compares with surgery, radiotherapy and active surveillance.

August 2026 Read →
NanoKnife IRE for prostate cancer — how irreversible electroporation works
Prostate Focal therapy New

NanoKnife uses precision electrical pulses to destroy prostate cancer cells by disrupting their membranes — without cutting, heating, or freezing. This article explains the IRE mechanism, who is a genuine candidate, and what the NICE position means in practice.

August 2026 Read →
Robotic colposuspension for stress urinary incontinence — explained
Female urology Incontinence New

Robotic colposuspension is a mesh-free keyhole operation that uses the same proven Burch principle with robotic precision. Written by Mr Denosshan Sri and Mr Jai Seth — who pioneered the procedure in the UK.

August 2026 Read →

Have a question about a urological condition?

Mr Sri sees patients at four London locations — Wimbledon, Cheam, Marylebone, and Kingston. Same-week appointments available. No GP referral required.