PSA Assessment · London
Raised PSA Specialist
London
Expert evaluation of elevated PSA by a consultant urological surgeon — including MRI prostate and targeted biopsy where needed. Same-week appointments available.
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QualificationMA Cantab · MB BChir · FRCS Urol
LocationsWimbledon · Cheam · Marylebone
ReferralsGP referral or self-referral accepted
InsuranceAll major insurers · Self-pay welcome
Important: A raised PSA does not always mean cancer — but it should never be ignored. Early specialist assessment can detect prostate cancer at a stage when treatment is most effective, and curative. If your GP has flagged an elevated PSA result, or if you are concerned about your prostate health, prompt specialist review is strongly advised.
What is PSA?
PSA (prostate-specific antigen) is a protein produced by the prostate gland. A small amount is normally present in the bloodstream, and a simple blood test can measure the level. PSA is not a perfect cancer marker — it can be raised for several reasons — but an elevated or rising PSA is an important signal that requires specialist assessment.
PSA testing is the most commonly used tool for detecting prostate cancer at an early, treatable stage. It is also used to monitor men already diagnosed with prostate conditions, and to track the response to treatment over time.
0–3
ng/ml · Normal range
Generally reassuring in younger men, though context and trend matter as much as the absolute value.
3–10
ng/ml · Borderline
Warrants specialist review. Around 1 in 4 men in this range will have prostate cancer on biopsy.
>10
ng/ml · Elevated
Risk of prostate cancer is significantly higher. Urgent urological assessment and MRI are indicated.
PSA ranges are age-dependent and should always be interpreted alongside clinical findings and PSA trend over time.
Why might PSA be raised?
An elevated PSA can have several causes. A thorough specialist assessment is the only reliable way to determine which is responsible.
Prostate cancer
The most important cause to exclude. Early-stage prostate cancer is often curable with the right treatment.
Benign prostatic hyperplasia (BPH)
An enlarged prostate — common in older men — naturally produces more PSA, even without cancer.
Prostatitis
Inflammation or infection of the prostate can cause PSA to rise significantly and temporarily.
Urinary tract infection
A UTI can transiently elevate PSA. Testing after treatment of infection may clarify the picture.
Recent physical activity
Vigorous exercise or sexual activity in the 48 hours before testing can cause a temporary PSA rise.
Rising PSA over time
A PSA that is rising on serial tests — even within the normal range — is a meaningful finding that warrants investigation.
How I assess a raised PSA
My approach to PSA assessment is thorough, evidence-based, and designed to give you clarity as quickly as possible. It follows current NICE, BAUS, and EAU guidelines.
1
Detailed consultation
A comprehensive review of your PSA history, urinary symptoms, family history (including first-degree relatives with prostate or breast cancer), and relevant risk factors including ethnicity. A digital rectal examination is offered where necessary.
2
Repeat PSA and additional blood tests
Where appropriate, a confirmatory PSA test and ratio measurements — including free:total PSA — help refine the cancer risk assessment before proceeding to imaging.
3
Multiparametric MRI (mpMRI) prostate
Multiparametric MRI of the prostate is now the standard of care prior to biopsy. It identifies suspicious areas, allows accurate risk stratification, and avoids unnecessary biopsy in men with a low-risk result. Some centres offer same day access to mpMRI via RAPID pathways
4
Targeted transperineal prostate biopsy
Where biopsy is required, I perform MRI-targeted transperineal biopsy under local or general anaesthetic. This approach — passing through the perineal skin rather than the rectum — is safer, reduces infection risk significantly, and improves the accuracy of cancer detection compared to older techniques.
5
Results, discussion, and next steps
All results are discussed with you in full at a dedicated follow-up appointment. If cancer is found, I will explain the grade and stage clearly, present all treatment options. All cases of confirmed cancer are referred to our multidisciplinary team. If the result is benign, a clear monitoring plan is agreed.
Mr Denosshan Sri
MA Cantab | MB BChir | FRCS Urol | Consultant Urological Surgeon
Mr Sri is a London consultant urological surgeon with subspecialist expertise in prostate and kidney cancer. He has particular experience in the surgical treatment of prostate cancer, including nerve-sparing robotic-assisted radical prostatectomy, and works closely with oncologists, urologists and radiologists as part of a multidisciplinary team. He offers comprehensive PSA assessment — from initial review through to MRI-targeted biopsy and definitive treatment — at three private hospital locations in London and Surrey.
Frequently asked questions
My PSA is only slightly raised — do I still need to see a specialist?
Yes. Even a modestly elevated PSA is worth investigating, particularly if it has risen from a previous result or if you have risk factors such as a family history of prostate cancer or African-Caribbean heritage. A specialist assessment will clarify the significance and guide whether further investigation is needed.
Is a raised PSA always a sign of cancer?
No. Many men with a raised PSA do not have prostate cancer — the elevation can be caused by benign enlargement, inflammation, or infection. However, cancer must be excluded through proper assessment. The purpose of specialist review is to determine the cause accurately, not to assume the worst.
What is an MRI-targeted biopsy and is it better than a standard biopsy?
Yes — MRI-targeted transperineal biopsy is now the recommended approach in NICE guidelines. By using MRI images to guide needle placement, it detects clinically significant cancers more reliably and avoids sampling areas of the prostate that are unlikely to contain cancer. The transperineal approach (through the skin, not the rectum) also significantly reduces the risk of post-biopsy infection.
How quickly can I be seen?
Same-week appointments are typically available. Given the importance of prompt assessment for a raised PSA, I aim to see patients as quickly as possible. MRI and biopsy can usually be arranged within a short timeframe thereafter.
Do I need a GP referral?
No — you can self-refer directly. Many patients come having seen their PSA result on a blood test report or private health screen and wish to discuss it without waiting for a GP appointment. A referral letter is helpful if available, but is not required.
What if prostate cancer is found?
If cancer is detected, I will explain the findings clearly and present all treatment options appropriate to your situation — including active surveillance for low-risk disease, robotic surgery, and radiotherapy. All cases are discussed at a cancer multidisciplinary meeting. Where surgery is the right choice, I specialise in nerve-sparing robotic-assisted radical prostatectomy where possible, which offers the best potential for functional recovery, and excellent functional outcomes.
Clinic locations
Mr Sri sees patients at three private hospital locations in and around London.
Spire St Anthony's
801 London Road
Cheam, Surrey
SM3 9DW
Tel: 020 8337 6691
Nuffield Parkside
53 Parkside
Wimbledon
SW19 5NX
Tel: 020 8971 8000
HCA Princess Grace
18 Devonshire Street
Marylebone, London
W1G 7AF
Tel: 020 379 77248
